Clozapine and aripiprazole?induced neutropenia
نویسندگان
چکیده
Neutropenia is a well-known adverse side-effect of clozapine that can also be seen with other atypical antipsychotics. In this article the authors discuss patient who experienced neutropenia and subsequently redeveloped aripiprazole after short trial. The case illustrates close monitoring caution advisable when trialing patients on any further antipsychotics neutropenic event clozapine.
منابع مشابه
Clozapine-Induced Febrile Neutropenia and Cellulitis
Clozapine is one of the atypical antipsychotics and is frequently prescribed to patients with treatment-resistant schizophrenia. Agranulocytosis is a major side effect that may lead to death, which limits its use. This is a case report of a patient that developed febrile neutropenia and cellulitis after treatment with clozapine for 20 weeks.
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C lozapine is an atypical antipsychotic that is effective in treatment resistant schizophrenia. The National Institute for Health and Clinical Excellence (NICE) guidelines for schizophrenia specify that ‘‘in individuals with evidence of treatment resistant schizophrenia, clozapine should be introduced at the earliest opportunity’’. A severe adverse effect of clozapine that limits its more wides...
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Clozapine is the antipsychotic of choice in the management of treatment resistant schizophrenia. Neutropenia is a rare but serious adverse effect of clozapine. The risk for neutropenia with clozapine is highest in the first 18 weeks of treatment and decreases with time though a few cases were reported after several years of continued therapy. Different protocols that guide the monitoring for ne...
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The atypical antipsychotic clozapine is very effective for treatment of schizophrenia, but it causes agranulocytosis requiring drug cessation in up to 2% of cases. There has been some success rechallenging with clozapine at a later date or giving granulocyte colony stimulating factor or lithium while continuing clozapine. However, there are still some patients for whom these strategies do not w...
متن کامل[Hematological alterations associated to olanzapine use after clozapine-induced neutropenia].
O presente re la to é compat íve l com a hipótese de Thangadurai et al. descrita acima, mas sugere que a susceptibilidade à neutropenia após exposição à clozapina pode ser transitória, de modo que o r isco hematológico da olanzapina decresceria à medida que o tempo decorrido após a suspensão da clozapina aumentasse. Sugerimos que pacientes que desenvolverem alterações hematológicas com clozapin...
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ژورنال
عنوان ژورنال: Progress in Neurology and Psychiatry
سال: 2023
ISSN: ['1931-227X', '1367-7543']
DOI: https://doi.org/10.1002/pnp.774